CALL FOR PAPERS Cell Signaling: Proteins, Pathways and Mechanisms Muscle RANK is a key regulator of Ca storage, SERCA activity, and function of fast-twitch skeletal muscles
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چکیده
Sébastien S. Dufresne,* Nicolas A. Dumont,* Antoine Boulanger-Piette, Val A. Fajardo, Daniel Gamu, Sandrine-Aurélie Kake-Guena, Rares Ovidiu David, Patrice Bouchard, Éliane Lavergne, Josef M. Penninger, Paul C. Pape, A. Russell Tupling, and Jérôme Frenette Centre Hospitalier Universitaire de Québec-Centre de Recherche du Centre Hospitalier de l’Université Laval, Université Laval, Quebec City, Quebec, Canada; Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada; Faculté de Médecine et des Sciences de la Santé, Département de Physiologie et Biophysique, Université de Sherbrooke, Sherbrooke, Québec, Canada; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria; and Faculté de Médecine, Département de Réadaptation, Université Laval, Quebec City, Quebec, Canada
منابع مشابه
Muscle RANK is a key regulator of Ca2+ storage, SERCA activity, and function of fast-twitch skeletal muscles.
Receptor-activator of nuclear factor-κB (RANK), its ligand RANKL, and the soluble decoy receptor osteoprotegerin are the key regulators of osteoclast differentiation and bone remodeling. Here we show that RANK is also expressed in fully differentiated myotubes and skeletal muscle. Muscle RANK deletion has inotropic effects in denervated, but not in sham, extensor digitorum longus (EDL) muscles ...
متن کاملEffect of progressive resistance exercise on β1 integrin and vinculin protein levels in slow-and fast-twitch skeletal muscles of male rats
Introduction: Skeletal muscle is a flexible and ever changing tissue and the role of costameric proteins in its response to different stimuli is not well defined. The aim of this study was to investigate the effect of progressive resistance exercise on β1 integrin and vinculin proteins in fast and slow twitch skeletal muscles of male rats. Methods: Twelve male Wistar rats (weight: 298±5.2 gr...
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Background and Objectives: Myocyte enhancer factor 2c activates the genes of the slow-twitch muscle, the muscle which plays role in endurance activity. Therefore, the aim of this study was to evaluate the effect of a program of intensive endurance activity on MEF2c gene expression in fast and slow twitch skeletal muscles in wistar rats. Materials and Methods: In this experimental study, 14 mal...
متن کاملThe Effect of High and Low-Intensity Interval Training on TRF1 and TRF2 Gene Expression in Slow and Fast-Twitch Skeletal Muscles of C57BL/6 Mice: An Experimental Study
Background and Objectives: The process of chronic diseases and aging is associated with reduced telomere length. The aim of this study was to investigate the effect of high-intensity interval training (HIIT) and low-intensity interval training (LIIT) on telomere repeat binding factor 1 and 2 (TRF1 and TRF2) in Soleus (SOL) muscle as a slow-twitch (ST) and Extensor Digitorum Longus (EDL) muscle ...
متن کاملMuscle RANK is a key regulator of calcium storage, SERCA activity, and function of fast-twitch skeletal muscles
Sébastien S. Dufresne, Nicolas A. Dumont, Antoine Boulanger-Piette, Val A. Fajardo, 4 Daniel Gamu, Sandrine-Aurélie Kake-Guena, Rares Ovidiu David, Patrice Bouchard, 5 Éliane Lavergne, Josef M. Penninger , Paul C. Pape, A. Russell Tupling and Jérôme 6 Frenette 7 1 Centre Hospitalier Universitaire de Québec–Centre de Recherche du Centre Hospitalier de 8 l’Université Laval (CHUQ-CRCHUL), Universi...
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تاریخ انتشار 2016